SubtiBank SubtiBank
spo0E [2018-02-12T02:16:33.000Z]
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spo0E [2018-02-12T02:16:33.000Z]

Spo0A-P phosphatase, control of the phosphorelay
locus
BSU13640
pI
6.48
mw
9.65 kDa
protein length
85 aa Sequence Blast
gene length
255 bp Sequence Blast
function
initiation of sporulation
product
Spo0A-P phosphatase
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.4|Protein phosphatases]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay] → [category|SW 3.4.7.5|Phosphatases controlling the phosphorelay]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay] → [category|SW 4.2.2.5|Phosphatases controlling the phosphorelay]

    • Gene

    Coordinates
    1,430,684 → 1,430,941

    The protein

    Protein family

  • spo0E family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|A2250786C40A23A5EBD830B3853DE5187B3D24EC|YnzD]

    • Expression and Regulation

    Operons

    genes
    [gene|A574974B6F4FF46DC69E03AE021651C67089866F|spo0E]
    description
    [Pubmed|2838724]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|1901567], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|22210769], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

    • regulatory mechanism

  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|2504584], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]
  • [protein|1508770D5BCA5739D13E3ABD11CC5C103C07FF25|Rok]: repression, of the [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]-dependent promoter [Pubmed|22524514], in [regulon|1508770D5BCA5739D13E3ABD11CC5C103C07FF25|Rok regulon]

    • regulation

  • induced under stress conditions ([protein|search|SigB]) [Pubmed|22210769]

    • additional information

  • Spo0E is degraded by [protein|search|FtsH]
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    Biological materials

    Mutant

  • BKE13640 (Δ[gene|A574974B6F4FF46DC69E03AE021651C67089866F|spo0E]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE13640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCACTTCACCCCTCGCC, downstream forward: _UP4_TAGCGGCCTATCAGATGCAT
  • BKK13640 (Δ[gene|A574974B6F4FF46DC69E03AE021651C67089866F|spo0E]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK13640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCACTTCACCCCTCGCC, downstream forward: _UP4_TAGCGGCCTATCAGATGCAT

    • Labs working on this gene/protein

  • [SW|Tony Wilkinson], York University, U.K. [http://www.york.ac.uk/depts/chem/staff/ajw.html homepage]

    • References

    Reviews

  • 19995980

    • Original publications

  • 2838724,1901567,8127878,11112444,11679073,12067336,15916600,15057450,17001075,18045868,19050850,19332814,22524514,22210769,2504584,22142536